Category: My publications

Related Articles Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers. J Psychopharmacol. 2019 Feb 28;:269881119827891 Authors: Erritzoe D, Smith J, Fisher PM, Carhart-Harris R, Frokjaer VG, Knudsen GM Abstract BACKGROUND:: Recent studies have suggested therapeutic benefits of psychedelics for a variety of mental health conditions.…

Front Psychol. 2019 Jan 11;9:2767. doi: 10.3389/fpsyg.2018.02767. eCollection 2018. ABSTRACT Allopregnanolone is a metabolite of the sex hormone progesterone, with suggested relevance for female mood disorders. While allopregnanolone and serotonin are known to influence psychological well-being, the molecular and psychological specifics of their relationship are to date poorly understood, especially in women of fertile age…

Hum Brain Mapp. 2019 May;40(7):2117-2124. doi: 10.1002/hbm.24511. Epub 2019 Jan 11. ABSTRACT Recent research found lasting increases in personality trait Openness in healthy individuals and patients after administration of the serotonin 2A receptor (5-HT2A R) agonist psilocybin. However, no studies have investigated whether 5-HT2A R availability as imaged using positron emission tomography (PET) is associated…

Related Articles Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age. Front Psychol. 2018;9:2767 Authors: Sundström Poromaa I, Comasco E, Bäckström T, Bixo M, Jensen P, Frokjaer VG Abstract Allopregnanolone is a metabolite of the sex hormone progesterone, with suggested relevance for female mood disorders. While allopregnanolone and serotonin…

Related Articles Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study. Hum Brain Mapp. 2019 Jan 11;: Authors: Stenbaek DS, Kristiansen S, Burmester D, Madsen MK, Frokjaer VG, Knudsen GM, Fisher PM Abstract Recent research found lasting increases in personality trait Openness in healthy individuals and patients after administration of…

Psychopharmacology (Berl). 2019 Jun;236(6):1759-1769. doi: 10.1007/s00213-018-5158-3. Epub 2019 Jan 8. ABSTRACT RATIONALE: The serotonergic system has been repeatedly linked to visual attention in general, but the effects of selective serotonin reuptake inhibitor (SSRI) on specific components of visual attention remain unknown. Changes in distinct perceptual and cognitive processes are not readily evident in most attention…

Related Articles Three weeks of SSRI administration enhances the visual perceptual threshold – a randomized placebo-controlled study. Psychopharmacology (Berl). 2019 Jan 08;: Authors: Lansner J, Jensen CG, Petersen A, Fisher PM, Frokjaer VG, Vangkilde S, Knudsen GM Abstract RATIONALE: The serotonergic system has been repeatedly linked to visual attention in general, but the effects of…

Br J Psychiatry. 2019 Sep;215(3):519-527. doi: 10.1192/bjp.2018.234. ABSTRACT BACKGROUND: Enhanced sensitivity to oestrogen signalling may drive increased risk for depressive symptoms when exposed to peripartum sex-steroid hormone fluctuations. AIM: Testing if 116 pre-identified sex steroid-responsive transcripts that predicted perinatal depression (PND) translates to a pharmacological model of hormone-induced mood changes. METHOD: We generated longitudinal, genome-wide…

Related Articles Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. Br J Psychiatry. 2018 Nov 20;:1-9 Authors: Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG Abstract BACKGROUND: Enhanced sensitivity to oestrogen signalling may drive increased risk for depressive symptoms when exposed to peripartum sex-steroid hormone fluctuations.AimTesting if…

Psychoneuroendocrinology. 2019 Jan;99:251-256. doi: 10.1016/j.psyneuen.2018.10.016. Epub 2018 Oct 26. ABSTRACT BACKGROUND: Women show increased risk of depressive symptoms during hormonal transition phases. The risk mechanisms may include changes in mood in response to fluctuating ovarian hormones moderated by predisposing risk factors for mood disorders, such as personality trait Neuroticism. METHODS: A pooled sample of 92…