Category: My publications

J Cereb Blood Flow Metab. 2020 Sep;40(9):1902-1911. doi: 10.1177/0271678X19880450. Epub 2019 Oct 1. ABSTRACT Positron emission tomography (PET) neuroimaging provides unique possibilities to study biological processes in vivo under basal and interventional conditions. For quantification of PET data, researchers commonly apply different arrays of sequential data analytic methods (“preprocessing pipeline”), but it is often unknown…

Related Articles Different preprocessing strategies lead to different conclusions: A [11C]DASB-PET reproducibility study. J Cereb Blood Flow Metab. 2019 Oct 01;:271678X19880450 Authors: Nørgaard M, Ganz M, Svarer C, Frokjaer VG, Greve DN, Strother SC, Knudsen GM Abstract Positron emission tomography (PET) neuroimaging provides unique possibilities to study biological processes in vivo under basal and interventional conditions.…

Related Articles Psychometric Properties and Validation of the EMOTICOM Test Battery in a Healthy Danish Population. Front Psychol. 2019;10:2660 Authors: Dam VH, Thystrup CK, Jensen PS, Bland AR, Mortensen EL, Elliott R, Sahakian BJ, Knudsen GM, Frokjaer VG, Stenbæk DS Abstract Disruptions in hot cognition, i.e., the processing of emotionally salient information, are prevalent in…

Neuroimage. 2019 Oct 1;199:466-479. doi: 10.1016/j.neuroimage.2019.05.055. Epub 2019 Jun 1. ABSTRACT Positron Emission Tomography (PET) is an important neuroimaging tool to quantify the distribution of specific molecules in the brain. The quantification is based on a series of individually designed data preprocessing steps (pipeline) and an optimal preprocessing strategy is per definition associated with less…

Related Articles Optimization of preprocessing strategies in Positron Emission Tomography (PET) neuroimaging: A [11C]DASB PET study. Neuroimage. 2019 Jun 01;: Authors: Nørgaard M, Ganz M, Svarer C, Frokjaer VG, Greve DN, Strother SC, Knudsen GM Abstract Positron Emission Tomography (PET) is an important neuroimaging tool to quantify the distribution of specific molecules in the brain.…

Acta Psychiatr Scand. 2019 Jul;140(1):77-84. doi: 10.1111/acps.13038. Epub 2019 May 24. ABSTRACT OBJECTIVES: Sensitivity to sex-steroid hormone fluctuations may increase risk for perinatal depression. We aimed to identify genome-wide biological profiles in women demonstrating sensitivity to pharmacological sex-hormone manipulation with gonadotrophin-releasing hormone agonist (GnRHa). METHODS: Longitudinal gene expression (Illumina Human HT12.v4) and DNA methylation data…

Related Articles Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms. Acta Psychiatr Scand. 2019 May 17;: Authors: Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG Abstract OBJECTIVES: Sensitivity to sex-steroid hormone fluctuations may increase risk for perinatal depression. We aimed to identify genome-wide biological…

Neuron. 2019 Apr 3;102(1):13-16. doi: 10.1016/j.neuron.2019.02.023. ABSTRACT Perinatal depression (PND) is a heterogeneous disorder with differences in timing of onset of depression, which influences symptomology, severity, and treatment efficacy. Researchers must embrace the heterogeneity to bring fruition to a precision medicine approach for women in reproductive mental health care. PMID:30946818 | DOI:10.1016/j.neuron.2019.02.023 Source: My publications…

Related Articles Perinatal Depression: Embracing Variability toward Better Treatment and Outcomes. Neuron. 2019 Apr 03;102(1):13-16 Authors: Galea LAM, Frokjaer VG Abstract Perinatal depression (PND) is a heterogeneous disorder with differences in timing of onset of depression, which influences symptomology, severity, and treatment efficacy. Researchers must embrace the heterogeneity to bring fruition to a precision medicine…

J Psychopharmacol. 2019 Sep;33(9):1068-1075. doi: 10.1177/0269881119827891. Epub 2019 Feb 28. ABSTRACT BACKGROUND: Recent studies have suggested therapeutic benefits of psychedelics for a variety of mental health conditions. The understanding of how single psychedelic administrations can induce long-lasting effects are, in large, still lacking. However, recent studies in both healthy and clinical populations suggest a role…