Tag: interview

Brain. 2016 May;139(Pt 5):1605-14. doi: 10.1093/brain/aww043. Epub 2016 Mar 19. ABSTRACT Cross-sectional neuroimaging studies in non-depressed individuals have demonstrated an inverse relationship between daylight minutes and cerebral serotonin transporter; this relationship is modified by serotonin-transporter-linked polymorphic region short allele carrier status. We here present data from the first longitudinal investigation of seasonal serotonin transporter fluctuations…

Psychoneuroendocrinology. 2016 Jun;68:39-46. doi: 10.1016/j.psyneuen.2016.02.023. Epub 2016 Feb 26. ABSTRACT BACKGROUND: Women show increased risk of depressive symptoms in life phases where ovarian steroid hormone levels fluctuate or decline rapidly. The risk mechanisms may include changes in mental state and affective cognition possibly mediated by serotonergic neurotransmission. METHODS: In a randomized controlled double-blinded trial, 61…

Psychoneuroendocrinology. 2016 May;67:124-32. doi: 10.1016/j.psyneuen.2016.01.032. Epub 2016 Feb 11. ABSTRACT Serotonin signalling is considered critical for an appropriate and dynamic adaptation to stress. Previously, we have shown that prefrontal serotonin transporter (SERT) binding is positively associated with the cortisol awakening response (CAR) (Frokjaer et al., 2013), which is an index of hypothalamic-pituitary-adrenal (HPA)-axis output dynamics.…

Related Articles Sex hormone manipulation slows reaction time and increases labile mood in healthy women. Psychoneuroendocrinology. 2016 Feb 26;68:39-46 Authors: Stenbæk DS, Fisher PM, Budtz-Jørgensen E, Pinborg A, Hjordt LV, Jensen PS, Knudsen GM, Frokjaer VG Abstract BACKGROUND: Women show increased risk of depressive symptoms in life phases where ovarian steroid hormone levels fluctuate or…

BMC Public Health. 2015 Dec 16;15:1245. doi: 10.1186/s12889-015-2588-2. ABSTRACT BACKGROUND: Prolonged psychological stress is a risk factor for illness and constitutes an increasing public health challenge creating a need to develop public interventions specifically targeting stress and promoting mental health. The present randomized controlled trial evaluated health effects of a novel program: Relaxation-Response-based Mental Health…

Open and Calm–a randomized controlled trial evaluating a public stress reduction program in Denmark. BMC Public Health. 2015;15:1245 Dec.16-2015 Authors: Jensen CG, Lansner J, Petersen A, Vangkilde SA, Ringkøbing SP, Frokjaer VG, Adamsen D, Knudsen GM, Denninger JW, Hasselbalch SG Abstract BACKGROUND: Prolonged psychological stress is a risk factor for illness and constitutes an increasing…

Eur Neuropsychopharmacol. 2016 Jan;26(1):147-149. doi: 10.1016/j.euroneuro.2015.11.010. Epub 2015 Nov 26. ABSTRACT Acute Tryptophan Depletion (ATD) is a dietary method used to modulate central 5-HT to study the effects of temporarily reduced 5-HT synthesis. The aim of this study is to evaluate a novel method of ATD using a gelatin-based collagen peptide (CP) mixture. We administered…

Transl Psychiatry. 2015 Dec 1;5(12):e688. doi: 10.1038/tp.2015.184. ABSTRACT Sex-hormone fluctuations may increase risk for developing depressive symptoms and alter emotional processing as supported by observations in menopausal and pre- to postpartum transition. In this double-blinded, placebo-controlled study, we used blood-oxygen level dependent functional magnetic resonance imaging (fMRI) to investigate if sex-steroid hormone manipulation with a…

Evaluation of acute tryptophan depletion and sham depletion with a gelatin-based collagen peptide protein mixture. Eur Neuropsychopharmacol. 2015 Nov 26; Authors: Stenbæk DS, Einarsdottir HS, Goregliad-Fjaellingsdal T, Knudsen GM, Frokjaer VG, Hasselbalch SG Abstract Acute Tryptophan Depletion (ATD) is a dietary method used to modulate central 5-HT to study the effects of temporarily reduced 5-HT…