Category: My publications
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Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study.
Role of Serotonin Transporter Changes in Depressive Responses to Sex-Steroid Hormone Manipulation: A Positron Emission Tomography Study. Biol Psychiatry. 2015 Apr 27; Authors: Frokjaer VG, Pinborg A, Holst KK, Overgaard A, Henningsson S, Heede M, Larsen EC, Jensen PS, Agn M, Nielsen AP, Stenbæk DS, da Cunha-Bang S, Lehel S, Siebner HR, Mikkelsen JD, Svarer…
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Functional connectivity of the dorsal and median raphe nuclei at rest.
Functional connectivity of the dorsal and median raphe nuclei at rest. Neuroimage. 2015 May 8; Authors: Beliveau V, Svarer C, Frokjaer VG, Knudsen GM, Greve DN, Fisher PM Abstract Serotonin (5-HT) is a neurotransmitter critically involved in a broad range of brain functions and implicated in the pathophysiology of neuropsychiatric illnesses including major depression, anxiety…
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The Center for Integrated Molecular Brain Imaging (Cimbi) Database.
The Center for Integrated Molecular Brain Imaging (Cimbi) Database. Neuroimage. 2015 Apr 16; Authors: Knudsen GM, Jensen PS, Erritzoe D, Baaré WF, Ettrup A, Fisher PM, Gillings N, Hansen HD, Hansen LK, Hasselbalch SG, Henningsson S, Herth MM, Holst KK, Iversen P, Kessing LV, Macoveanu J, Madsen KS, Mortensen EL, Nielsen FÅ, Paulson OB, Siebner…
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The Center for Integrated Molecular Brain Imaging (Cimbi) database
Neuroimage. 2016 Jan 1;124(Pt B):1213-1219. doi: 10.1016/j.neuroimage.2015.04.025. Epub 2015 Apr 17. ABSTRACT We here describe a multimodality neuroimaging containing data from healthy volunteers and patients, acquired within the Lundbeck Foundation Center for Integrated Molecular Brain Imaging (Cimbi) in Copenhagen, Denmark. The data is of particular relevance for neurobiological research questions related to the serotonergic transmitter…
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Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial.
Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial. Anesthesiology. 2015 Apr;122(4):884-94 Authors: Lunn TH, Frokjaer VG, Hansen TB, Kristensen PW, Lind T, Kehlet H Abstract BACKGROUND: Sufficient pain treatment remains a challenge after total knee arthroplasty (TKA), especially in high pain catastrophizing patients. Serotonergic…
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Analgesic effect of perioperative escitalopram in high pain catastrophizing patients after total knee arthroplasty: a randomized, double-blind, placebo-controlled trial
Anesthesiology. 2015 Apr;122(4):884-94. doi: 10.1097/ALN.0000000000000597. ABSTRACT BACKGROUND: Sufficient pain treatment remains a challenge after total knee arthroplasty (TKA), especially in high pain catastrophizing patients. Serotonergic signaling may be involved in pain processing, but the effect of selective serotonin reuptake inhibitors on well-defined postoperative pain has not previously been investigated. The authors hypothesized that perioperative escitalopram…
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Fluctuations in [(11)C]SB207145 PET Binding Associated with Change in Threat-Related Amygdala Reactivity in Humans.
Fluctuations in [(11)C]SB207145 PET Binding Associated with Change in Threat-Related Amygdala Reactivity in Humans. Neuropsychopharmacology. 2015 Jan 6; Authors: Fisher PM, Ewers Haahr M, Jensen CG, Frokjaer VG, Siebner HR, Knudsen GM Abstract Serotonin critically affects the neural processing of emotionally salient stimuli, including indices of threat, but how alterations in serotonin signaling contribute to…
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Fluctuations in [¹¹C]SB207145 PET binding associated with change in threat-related amygdala reactivity in humans
Neuropsychopharmacology. 2015 May;40(6):1510-8. doi: 10.1038/npp.2014.339. Epub 2015 Jan 6. ABSTRACT Serotonin critically affects the neural processing of emotionally salient stimuli, including indices of threat; however, how alterations in serotonin signaling contribute to changes in brain function is not well understood. Recently, we showed in a placebo-controlled study of 32 healthy males that brain serotonin 4…
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Functional and molecular neuroimaging of menopause and hormone replacement therapy.
Functional and molecular neuroimaging of menopause and hormone replacement therapy. Front Neurosci. 2014;8:388 Authors: Comasco E, Frokjaer VG, Sundström-Poromaa I Abstract The level of gonadal hormones to which the female brain is exposed considerably changes across the menopausal transition, which in turn, is likely to be of great relevance for neurodegenerative diseases and psychiatric disorders.…
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BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels.
Related Articles BDNF Val66met and 5-HTTLPR polymorphisms predict a human in vivo marker for brain serotonin levels. Hum Brain Mapp. 2015 Jan;36(1):313-23 Authors: Fisher PM, Holst KK, Adamsen D, Klein AB, Frokjaer VG, Jensen PS, Svarer C, Gillings N, Baare WF, Mikkelsen JD, Knudsen GM Abstract Brain-derived neurotrophic factor (BDNF) has been implicated in multiple…