Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape

Transl Psychiatry. 2021 Mar 4;11(1):155. doi: 10.1038/s41398-021-01270-5. ABSTRACT Maternal postpartum depression (PPD) is a significant public health concern due to the severe negative impact on maternal and child health and well-being. In this study, we aimed to identify genes associated with PPD. To do this, we investigated genome-wide gene expression profiles of pregnant women during […]? →Read more

Associations between the cortisol awakening response and patient-evaluated stress and mood instability in patients with bipolar disorder: an exploratory study

Int J Bipolar Disord. 2021 Mar 1;9(1):8. doi: 10.1186/s40345-020-00214-0. ABSTRACT OBJECTIVE: The Cortisol Awakening Response (CAR) measured as the transient increase in cortisol levels following morning awakening appears to be a distinct feature of the HPA axis. Patients with bipolar disorder (BD) experience daily stress, mood instability (MI) and studies have shown disrupted HPA-axis dynamics. […]? →Read more

Reward processing in major depressive disorder and prediction of treatment response – Neuropharm study

Eur Neuropsychopharmacol. 2021 Mar;44:23-33. doi: 10.1016/j.euroneuro.2020.12.010. Epub 2021 Jan 15. ABSTRACT Major depressive disorder (MDD) is a prevalent brain disorder for which anhedonia is a core symptom, indicating aberrations in the neural processing of reward. The striatum, medial prefrontal cortex (mPFC) and anterior insula (AI) are core reward processing regions. Here we used a reward-related, […]? →Read more

Reward processing in major depressive disorder and prediction of treatment response – Neuropharm study.

Related Articles Reward processing in major depressive disorder and prediction of treatment response – Neuropharm study. Eur Neuropsychopharmacol. 2021 Jan 14;: Authors: Brandt IM, Köhler-Forsberg K, Ganz M, Ozenne B, Jorgensen MB, Poulsen A, Knudsen GM, Frokjaer VG, Fisher PM Abstract Major depressive disorder (MDD) is a prevalent brain disorder for which anhedonia is a […]? →Read more

Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women

Acta Psychiatr Scand. 2020 Oct;142(4):294-306. doi: 10.1111/acps.13211. Epub 2020 Jul 21. ABSTRACT OBJECTIVE: Sex steroid hormones potently shape brain functions, including those critical to maintain mental health such as serotonin signaling. Use of oral contraceptives (OCs) profoundly changes endogenous sex steroid hormone levels and dynamics. Recent register-based studies show that starting an OC is associated […]? →Read more

Cognitive processing of infant stimuli in pregnant women with and without affective disorders and the association to postpartum depression

Eur Neuropsychopharmacol. 2021 Jan;42:97-109. doi: 10.1016/j.euroneuro.2020.10.006. Epub 2020 Nov 3. ABSTRACT Pregnancy and childbirth are among the strongest risk factors for depression but the neurocognitive mechanisms underlying this enhanced risk are unknown. This study investigated emotional and non-emotional cognition in 57 pregnant women with or without an affective disorder during their third trimester, and the […]? →Read more

Cognitive processing of infant stimuli in pregnant women with and without affective disorders and the association to postpartum depression.

Related Articles Cognitive processing of infant stimuli in pregnant women with and without affective disorders and the association to postpartum depression. Eur Neuropsychopharmacol. 2020 Nov 03;: Authors: Bjertrup AJ, Jensen MB, Schjødt MS, Parsons CE, Kjærbye-Thygesen A, Mikkelsen RL, Moszkowicz M, Frøkjær VG, Vinberg M, Kessing LV, Væver MS, Miskowiak KW Abstract Pregnancy and childbirth […]? →Read more

Podcast interview from Weekendavisen about estrogen and the brain – in Danish

  Østrogen og skarpe hjerner   Listen her: Source: https://www.weekendavisen.dk/2020-39/24spoergsmaal/oestrogen-og-skarpe-hjerner →Read more

Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women.

Related Articles Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women. Acta Psychiatr Scand. 2020 Oct;142(4):294-306 Authors: Larsen SV, Köhler-Forsberg K, Dam VH, Poulsen AS, Svarer C, Jensen PS, Knudsen GM, Fisher PM, Ozenne B, Frokjaer VG Abstract OBJECTIVE: Sex steroid hormones potently shape brain functions, including those critical […]? →Read more

Effect of supervised group exercise on psychological well-being among pregnant women with or at high risk of depression (the EWE Study): A randomized controlled trial

Acta Obstet Gynecol Scand. 2021 Jan;100(1):129-138. doi: 10.1111/aogs.13982. Epub 2020 Sep 15. ABSTRACT INTRODUCTION: Depression is expected to be the leading cause of disability worldwide by 2030. The prevalence is increasing and is two-fold higher in women than in men, women being at particularly high risk during hormonal transition phases such as pregnancy and the […]? →Read more